Article

Ticagrelor responsive platelet genes are associated with platelet function and bleeding

2022-03-18

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Importance</h4> Ticagrelor inhibits platelet function, prevents myocardial infarction, and causes bleeding. A comprehensive analysis of the on- and off-target platelet effects of ticagrelor that underlie its clinical effects is lacking. <h4>Objective</h4> To test the hypothesis that platelet transcripts that change in response to ticagrelor exposure are associated with platelet fun...

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Literature Corpus work: b7ea7334-3b56-521c-85a1-97320702745d
DOI: 10.1101/2022.03.18.22270280

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