Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic mutations in PEAR1 associated with cardiovascular outcomes in Chinese patients with acute coronary syndrome.

Thrombosis research - 1 Mar 2018

Nie Xiao-Yan, Li Jun-Lei, Qin Si-Bei, Fu Yu, Liang Guang-Kai, Shi Lu-Wen, Shao Hong, Liu Jian, Lu Yun

Abstract excerpt

OBJECTIVE: To investigate the association between PEAR1 (platelet endothelial aggregation receptor-1) polymorphisms and cardiovascular outcomes in acute coronary syndrome (ACS) in patients treated with aspirin and clopidogrel. METHODS: We genotyped eight common PEAR1 SNPs (rs2768759, rs12566888, rs12041331, rs11264579, rs2644592, , , and ), also CYP2C19*2 () and CYP2C19*3...

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Coronary Syndrome
Share to Adolescent
Share to Aged, 80 and over
Share to Asian People
Share to Cardiovascular Diseases
Share to Receptors, Cell Surface
Share to Treatment Outcome
Share to Young Adult

Source

Identifiers

PMID: 29407631
DOI: 10.1016/j.thromres.2018.01.026

Genes

PEAR1
PIR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic mutations in PEAR1 associated with cardiovascular outcomes in Chinese patients with acute coronary syndrome.PMID 29407631Read ↗

Association of PEAR1 genetic variants with platelet reactivity in response to dual antiplatelet therapy with aspirin and clopidogrel in the Chinese patient population after percutaneous coronary intervention.Semantic proximity Read ↗

Effect of PEAR1 Genetic Variants on 1-Year Outcomes in Chinese Patients with Acute Myocardial Infarction After Percutaneous Coronary Intervention.Semantic proximity Read ↗

Genetic Variants of PEAR1 are Associated with Platelet Function and Antiplatelet Drug Efficacy: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes.Semantic proximity Read ↗

Genetic variants of PEAR1 and ischemic clinical outcomes in coronary artery disease patients: a systematic review and meta-analysis.Semantic proximity Read ↗

Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients.Semantic proximity Read ↗

Identification of PEAR1 SNPs and their influences on the variation in prasugrel pharmacodynamics.Semantic proximity Read ↗

Effect of PEAR1, PTGS1 gene polymorphisms on the recurrence of aspirin-treated patients with ischemic stroke in the Han population of China: A 4-year follow-up study.Semantic proximity Read ↗

Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy.Semantic proximity Read ↗

Effects of four novel genetic polymorphisms on clopidogrel efficacy in Chinese acute coronary syndromes patients.Semantic proximity Read ↗

A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability.Semantic proximity Read ↗

Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.