Article
Myeloid peroxisome proliferator-activated receptor gamma deficiency aggravates myocardial infarction in mice.
Atherosclerosis - 1 Jul 2018
Shen Zhu-Xia, Yang Qing-Zhen, Li Chao, Du Lin-Juan, Sun Xue-Nan, Liu Yan, Sun Jian-Yong, Gu Hui-Hui, Sun Yu-Min, Wang Jun, Duan Sheng-Zhong
Abstract excerpt
BACKGROUND AND AIMS: Agonists of peroxisome proliferator-activated receptor gamma (Pparγ) have been demonstrated to reduce the risk of myocardial infarction (MI) in clinical trials and animal experiments. However, the cellular and molecular mechanisms are not completely understood. We aimed to reveal the functions of myeloid Pparγ in MI and explore the potential mechanisms in this study. METHODS: Myeloid Pparγ...
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