Article

CD206<sup>+</sup>IL-4Rα<sup>+</sup>MACROPHAGES ARE DRIVERS OF ADVERSE CARDIAC REMODELING IN ISCHEMIC CARDIOMYOPATHY

2024-10-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Cardiac CD206 + macrophages expand acutely after myocardial infarction (MI) to promote wound healing; however, their role in chronic heart failure (HF) is unknown. We tested the hypothesis that cardiac CD206 + macrophages expressing interleukin(IL)-4Rα are key drivers of adverse left ventricular (LV) remodeling in HF. <h4>METHODS AND RESULTS</h4> Adult male C57BL/6 mice underw...

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Literature Corpus work: 486b4003-238c-5de7-9c85-019b96cc9b70
DOI: 10.1101/2024.10.01.24314741

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