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Article

Atorvastatin attenuates sympathetic hyperinnervation together with the augmentation of M2 macrophages in rats postmyocardial infarction.

Cardiovascular therapeutics - 1 Aug 2016

Yang Na, Cheng Wenjuan, Hu Hesheng, Xue Mei, Li Xiaolu, Wang Ye, Xuan Yongli, Li Xinran, Yin Jie, Shi Yugen, Yan Suhua

Abstract excerpt

OBJECTIVES: Inflammation after myocardial infarction (MI) causes cardiac nerve sprouting and consequent ventricular arrhythmias (VAs). Macrophages, as major immune cells, are involved in the entire inflammation response process and serve as a link between inflammation and sympathetic hyperinnervation by regulating nerve growth factor (NGF) expression. Accumulating evidence shows that statins possess...

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Source

Identifiers

PMID: 27149420
DOI: 10.1111/1755-5922.12193

Genes

NGF
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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