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Article

CXADR-like membrane protein protects against heart injury by preventing excessive pyroptosis after myocardial infarction.

Journal of cellular and molecular medicine - 1 Dec 2020

Han Xinglong, Zhao Zhen-Ao, Yan Shiping, Lei Wei, Wu Hongchun, Lu Xing-Ai, Chen Yueqiu, Li Jingjing, Wang Yaning, Yu Miao, Wang Yongming, Zheng Yufang, Wang Hongyan, Shen Zhenya, Hu Shijun

Abstract excerpt

Myocardial infarction (MI) results in cardiomyocyte death and ultimately leads to heart failure. Pyroptosis is a type of the inflammatory programmed cell death that has been found in various diseased tissues. However, the role of pyroptosis in MI heart remains unknown. Here, we showed that CXADR-like membrane protein (CLMP) was involved in pyroptosis in the mouse MI heart. Our data showed that CLMP was strongly...

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Identifiers

PMID: 33084169
DOI: 10.1111/jcmm.15955
PMCID: PMC7753842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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