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Article

Genomic variants in an inbred mouse model predict mania-like behaviors.

PloS one - 1 Jan 2018

Saul Michael C, Stevenson Sharon A, Zhao Changjiu, Driessen Terri M, Eisinger Brian E, Gammie Stephen C

Abstract excerpt

Contemporary rodent models for bipolar disorders split the bipolar spectrum into complimentary behavioral endophenotypes representing mania and depression. Widely accepted mania models typically utilize single gene transgenics or pharmacological manipulations, but inbred rodent strains show great potential as mania models. Their acceptance is often limited by the lack of genotypic data needed to establish...

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PMID: 29768498
DOI: 10.1371/journal.pone.0197624
PMCID: PMC5955540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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