Article

Genome wide association analysis in a mouse advanced intercross line

2017-12-08

Abstract excerpt

The LG/J x SM/J advanced intercross line of mice ( LG x SM AIL ) is a multigenerational outbred population. High minor allele frequencies, a simple genetic background, and the fully sequenced LG and SM genomes make it a powerful population for genome-wide association studies. Here we use 1,063 AIL mice to identify 126 significant associations for 50 traits relevant to human health and disease. We also identify th...

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Literature Corpus work: 8ec3efe9-0305-5bc9-978f-d3d9c4aba6a2
DOI: 10.1101/230920

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