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Article

Studies in humans and mice implicate neurocan in the etiology of mania.

The American journal of psychiatry - 1 Sept 2012

Miró Xavier, Meier Sandra, Dreisow Marie Luise, Frank Josef, Strohmaier Jana, Breuer René, Schmäl Christine, Albayram Önder, Pardo-Olmedilla María Teresa, Mühleisen Thomas W, Degenhardt Franziska A, Mattheisen Manuel, Reinhard Iris, Bilkei-Gorzo Andras, Cichon Sven, Seidenbecher Constanze, Rietschel Marcella, Nöthen Markus M, Zimmer Andreas

Abstract excerpt

OBJECTIVE: Genome-wide association has been reported between the NCAN gene and bipolar disorder. The aims of this study were to characterize the clinical symptomatology most strongly influenced by NCAN and to explore the behavioral phenotype of Ncan knockout (Ncan(-/-)) mice. METHOD: Genotype/phe...

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Source

Identifiers

PMID: 22952076
DOI: 10.1176/appi.ajp.2012.11101585

Genes

NCAN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22952076-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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