Article
Turning strains into strengths for understanding psychiatric disorders.
Molecular psychiatry - 1 Dec 2020
Moore Shannon J, Murphy Geoffrey G, Cazares Victor A
Abstract excerpt
There is a paucity in the development of new mechanistic insights and therapeutic approaches for treating psychiatric disease. One of the major challenges is reflected in the growing consensus that risk for these diseases is not determined by a single gene, but rather is polygenic, arising from the action and interaction of multiple genes. Canonically, experimental models in mice have been designed to ascertain...
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