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Article

Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer's disease.

Scientific reports - 8 May 2018

Grace Christopher, Clarke Robert, Goel Anuj, Farrall Martin, Watkins Hugh, Hopewell Jemma C

Abstract excerpt

Epidemiological studies suggest a positive association between coronary artery disease (CAD) and late-onset Alzheimer's disease (LOAD). This large-scale genetic study brings together 'big data' resources to examine the causal impact of genetic determinants of CAD on risk of LOAD. A two-sample Mendelian randomization approach was adopted to estimate the causal effect of CAD on risk of LOAD using summary data from...

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Source

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Identifiers

PMID: 29740026
DOI: 10.1038/s41598-018-25460-2
PMCID: PMC5940751

Genes

CAD
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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