Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating Genetic Overlap between Alzheimer's Disease, Lipids, and Coronary Artery Disease: A Large-Scale Genome-Wide Cross Trait Analysis.

International journal of molecular sciences - 13 Aug 2024

Kirby Artika, Porter Tenielle, Adewuyi Emmanuel O, Laws Simon M

Abstract excerpt

There is evidence to support a link between abnormal lipid metabolism and Alzheimer's disease (AD) risk. Similarly, observational studies suggest a comorbid relationship between AD and coronary artery disease (CAD). However, the intricate biological mechanisms of AD are poorly understood, and its relationship with lipids and CAD traits remains unresolved. Conflicting evidence further underscores the ongoing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Lipid Metabolism

Share to Lipids

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 39201500
DOI: 10.3390/ijms25168814
PMCID: PMC11354907

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating Genetic Overlap between Alzheimer's Disease, Lipids, and Coronary Artery Disease: A Large-Scale Genome-Wide Cross Trait Analysis.PMID 39201500Read ↗

Investigating genetic overlap between Alzheimer's disease, lipids, and coronary artery disease: a large-scale genome-wide cross trait analysisSemantic proximity Read ↗

Exome-Wide Association Study Identified Clusters of Pleiotropic Genetic Associations with Alzheimer's Disease and Thirteen Cardiovascular Traits.Semantic proximity Read ↗

Lipid associated polygenic enrichment in Alzheimer’s diseaseSemantic proximity Read ↗

Shared genetic architecture between metabolic traits and Alzheimer’s disease: a large-scale genome-wide cross-trait analysisSemantic proximity Read ↗

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimer’s disease riskSemantic proximity Read ↗

Local genetic covariance analysis with lipid traits identifies novel loci for early-onset Alzheimer’s DiseaseSemantic proximity Read ↗

Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traitsSemantic proximity Read ↗

Is the Relationship Between Cardiovascular Disease and Alzheimer's Disease Genetic? A Scoping Review.Semantic proximity Read ↗

Integrative genetic analysis reveals shared genetic architecture underlying coronary artery disease, CT-Defined coronary atherosclerosis, and cardiometabolic risk factors.Semantic proximity Read ↗

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.Semantic proximity Read ↗

Multi-trait association studies discover pleiotropic loci between Alzheimer's disease and cardiometabolic traits.Semantic proximity Read ↗

Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.