Concordance of genetic determinants of acute coronary artery disease between European and Chinese populations.

doi:10.1093/gigascience/giag084

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Article

Concordance of genetic determinants of acute coronary artery disease between European and Chinese populations.

GigaScience - 21 Jan 2026

Edris Ahmed, Lin Kuang, Massa Sofia, Turnbull Iain, Millwood Iona Y, Sherliker Paul, Li Liming, Lv Jun, Yu Canqing, Sun Dianjianyi, Pei Pei, Avery Daniel, Liu Fang, Goel Anuj, Watkins Hugh, Chen Zhengming, Walters Robin G, Bennett Derrick A, Clarke Robert

Abstract excerpt

AIMS: This study examined the concordance of associations of single nucleotide polymorphisms (SNPs) for acute coronary artery disease (CAD) discovered in Europeans with acute CAD, chronic ischaemic heart disease (IHD) or stroke in Chinese adults. METHODS: In a nested case-control study of acute CAD (4,748 cases/66,227 controls) in China Kadoorie Biobank (CKB), we compared associations of 224 SNPs for acute CAD...

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Topics

Aged
Female
Humans
Male
Middle Aged
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

China

Coronary Artery Disease

Genetic Predisposition to Disease

Genetic Risk Score

Polymorphism, Single Nucleotide

Risk Factors

Stroke

White People

East Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 42578953
DOI: 10.1093/gigascience/giag084
PMCID: PMC13543311

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