Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II.

Molecular and cellular biology - 1 Jul 2018

Zeng Fanli, Hua Yu, Liu Xiaoqin, Liu Sijie, Lao Kejing, Zhang Ze, Kong Daochun

Abstract excerpt

RNA polymerase II (RNAPII) is one of the central enzymes in cell growth and organizational development. It is a large macromolecular complex consisting of 12 subunits. Relative to the clear definition of RNAPII structure and biological function, the molecular mechanism of how RNAPII is assembled is poorly understood, and thus the key assembly factors acting for the assembly of RNAPII remain elusive. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GTP Phosphohydrolases
Share to Monomeric GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Multiprotein Complexes

Share to Protein Multimerization

Share to Protein Subunits

Share to RNA Polymerase II

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 29661922
DOI: 10.1128/MCB.00091-18
PMCID: PMC6002695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II.PMID 29661922Read ↗

Rba50 and Gpn2 recruit the second largest subunits for the assembly of RNA polymerase II and III.Semantic proximity Read ↗

Npa3 interacts with Gpn3 and assembly factor Rba50 for RNA polymerase II biogenesis.Semantic proximity Read ↗

Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes.Semantic proximity Read ↗

Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II.Semantic proximity Read ↗

In-depth Analysis of the Lid Subunits Assembly Mechanism in MammalsSemantic proximity Read ↗

Dosage suppressors of gpn2ts mutants and functional insights into the role of Gpn2 in budding yeast.Semantic proximity Read ↗

Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103HSemantic proximity Read ↗

Unstructured N terminus of the RNA polymerase II subunit Rpb4 contributes to the interaction of Rpb4.Rpb7 subcomplex with the core RNA polymerase II of Saccharomyces cerevisiae.Semantic proximity Read ↗

An update on complex I assembly: the assembly of players.Semantic proximity Read ↗

Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining.Semantic proximity Read ↗

The Intriguing Mystery of RPA Phosphorylation in DNA Double-Strand Break RepairSemantic proximity Read ↗

Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.