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Article

Npa3 interacts with Gpn3 and assembly factor Rba50 for RNA polymerase II biogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2020

Liu Xueqin, Xie Debao, Hua Yu, Zeng Pei, Ma Lujie, Zeng Fanli

Abstract excerpt

RNA polymerase II is one of the most vital macromolecular complexes in eukaryotes and the assembly of such complete enzyme requires many factors. Three members of GPN-loop GTPase family Npa3/Gpn1, Gpn2, and Gpn3 participate in the biogenesis of RNA polymerase II with nonredundant roles. We show here that rapid degradation of each GPN protein in yeast leads to cytoplasmic accumulation of Rpb1 and defects in the...

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PMID: 32985767
DOI: 10.1096/fj.202001523R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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