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Article

Rba50 and Gpn2 recruit the second largest subunits for the assembly of RNA polymerase II and III.

International journal of biological macromolecules - 15 Apr 2022

Xie Debao, Zhao Xiangdong, Ma Lujie, Wang Le, Li Pan, Cheng Hongqian, Li Zhaoying, Zeng Pei, Zhang Jing, Zeng Fanli

Abstract excerpt

Although remarkable progress has been made toward understanding the structures of eukaryotic RNA polymerases, the pathways and factors that facilitate their assembly remain unresolved. Essential proteins Rba50 and Gpn2 are required for Rpb3 subcomplex assembly, but whether they participate in subsequent assembly steps is unknown. Herein, we performed comprehensive genetic screens to explore Rba50 function. We...

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PMID: 35176321
DOI: 10.1016/j.ijbiomac.2022.02.052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rba50 and Gpn2 recruit the second largest subunits for the assembly of RNA polymerase II and III.PMID 35176321Read ↗

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