Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.

The Journal of clinical investigation - 1 Jun 2018

Bao Li, Qian Zhaoyang, Lyng Maria B, Wang Ling, Yu Yuan, Wang Ting, Zhang Xiuqing, Yang Huanming, Brünner Nils, Wang Jun, Ditzel Henrik J

Abstract excerpt

Single cancer cell-sequencing studies currently use randomly selected cells, limiting correlations among genomic aberrations, morphology, and spatial localization. We laser-captured microdissected single cells from morphologically distinct areas of primary breast cancer and corresponding lymph node metastasis and performed whole-exome or deep-target sequencing of more than 100 such cells. Two major subclones...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to High-Throughput Nucleotide Sequencing

Share to Lymph Nodes

Share to Lymphatic Metastasis

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 29558370
DOI: 10.1172/JCI97449
PMCID: PMC5983317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.PMID 29558370Read ↗

Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasisSemantic proximity Read ↗

Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer.Semantic proximity Read ↗

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.Semantic proximity Read ↗

Single-cell transcriptomics provide insight into metastasis-related subsets of breast cancerSemantic proximity Read ↗

Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence.Semantic proximity Read ↗

Genome profiles of lymphovascular breast cancer cells reveal multiple clonally differentiated outcomes with multi-regional LCM and G&T-seqSemantic proximity Read ↗

Revisiting multifocal breast cancer: a clonality study of ductal carcinoma using whole exome sequencing.Semantic proximity Read ↗

Next-Generation Sequencing of Disseminated Tumor CellsSemantic proximity Read ↗

Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes.Semantic proximity Read ↗

Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.Semantic proximity Read ↗

Changes of Mutations and Copy-number and Enhanced Cell Migration during Breast TumorigenesisSemantic proximity Read ↗

Genomic alterations and evolution of cell clusters in metastatic invasive micropapillary carcinoma of the breastSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.