Article

Changes of Mutations and Copy-number and Enhanced Cell Migration during Breast Tumorigenesis

2022-03-28

Abstract excerpt

Although cancer stem cells (CSCs) play a major role in tumorigenesis and metastasis, the role of genetic alterations in invasiveness of CSCs is still unclear. Tumor microenvironment signals, such as extracellular matrix (ECM) composition, significantly influence cell behaviors. Unfortunately, these signals are often lost in in vitro cell culture. This study determines putative CSC populations, examines genetic ch...

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Literature Corpus work: 03d31f02-4772-509b-95f2-d15391c3e641
DOI: 10.1101/2022.03.27.485986

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