Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.

Cell - 11 Jan 2018

Casasent Anna K, Schalck Aislyn, Gao Ruli, Sei Emi, Long Annalyssa, Pangburn William, Casasent Tod, Meric-Bernstam Funda, Edgerton Mary E, Navin Nicholas E

Abstract excerpt

Ductal carcinoma in situ (DCIS) is an early-stage breast cancer that infrequently progresses to invasive ductal carcinoma (IDC). Genomic evolution has been difficult to delineate during invasion due to intratumor heterogeneity and the low number of tumor cells in the ducts. To overcome these challenges, we developed Topographic Single Cell Sequencing (TSCS) to measure genomic copy number profiles of single tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Clonal Evolution

Share to Neoplasm Invasiveness

Share to Sequence Analysis, DNA

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 29307488
DOI: 10.1016/j.cell.2017.12.007
PMCID: PMC5766405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.PMID 29307488Read ↗

Genome evolution in ductal carcinoma in situ: invasion of the clonesSemantic proximity Read ↗

Single-Cell Sequencing: Genomic and Transcriptomic Approaches in Cancer Cell BiologySemantic proximity Read ↗

Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Complex Genotypic-Phenotypic Relationships Altering Epithelial CompositionSemantic proximity Read ↗

Reconstructing mutational lineages in breast cancer by multi-patient-targeted single cell DNA sequencingSemantic proximity Read ↗

Single Cell Sequencing: Genomic and Transcriptomics Approaches in Cancer Cell BiologySemantic proximity Read ↗

Single-Cell Expression Analysis of Ductal Carcinoma In Situ Identifies Complex Genotypic-Phenotypic Relationships Altering Epithelial Composition.Semantic proximity Read ↗

Resolving the immune response across clonal cancer evolution in situ with whole transcriptome profilingSemantic proximity Read ↗

Current Progresses of Single Cell DNA Sequencing in Breast Cancer ResearchSemantic proximity Read ↗

Recent progress and applications of single-cell sequencing technology in breast cancerSemantic proximity Read ↗

Genomic profiling defines variable clonal relatedness between invasive breast cancer and primary ductal carcinoma <i>in situ</i>Semantic proximity Read ↗

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.Semantic proximity Read ↗

The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.