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Article

Next-Generation Sequencing of Disseminated Tumor Cells

1 Jan 2013

Abstract excerpt

Disseminated tumor cells (DTCs) detected in the bone marrow have been shown as an independent prognostic factor for women with breast cancer. However, the mechanisms behind the tumor cell dissemination are still unclear and more detailed knowledge is needed to fully understand why some cells remain dormant and others metastasize. Sequencing of single cells has opened for the possibility to dissect the genetic...

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Identifiers

PMID: 24427740
DOI: 10.3389/fonc.2013.00320

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