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Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and Cancer

26 Feb 2018

Abstract excerpt

Protein phosphorylation is a ubiquitous cellular process that allows for the nuanced and reversible regulation of protein activity. Protein phosphatase 2A (PP2A) is a heterotrimeric serine-threonine phosphatase-composed of a structural, regulatory, and catalytic subunit-that controls a variety of cellular events via protein dephosphorylation. While much is known about PP2A and its basic biochemistry, the...

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PMID: 29495399
DOI: 10.3390/genes9030121

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