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Article

All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.

The FEBS journal - 1 Mar 2016

Sangodkar Jaya, Farrington Caroline C, McClinch Kimberly, Galsky Matthew D, Kastrinsky David B, Narla Goutham

Abstract excerpt

Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase involved in the regulation of many cellular processes. A confirmed tumor suppressor protein, PP2A is genetically altered or functionally inactivated in many cancers highlighting a need for its therapeutic reactivation. In this review we discuss recent literature on PP2A: the elucidation of its structure and the functions of its subunits, and the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26507691
DOI: 10.1111/febs.13573
PMCID: PMC4803620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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