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TGF ‐β cascade regulation by PPP 1 and its interactors –impact on prostate cancer development and therapy

15 Mar 2014

Abstract excerpt

Protein phosphorylation is a key mechanism by which normal and cancer cells regulate their main transduction pathways. Protein kinases and phosphatases are precisely orchestrated to achieve the (de)phosphorylation of candidate proteins. Indeed, cellular health is dependent on the fine-tune of phosphorylation systems, which when deregulated lead to cancer. Transforming growth factor beta (TGF-β) pathway...

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PMID: 24629090
DOI: 10.1111/jcmm.12266

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