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Article

Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors

1 Oct 2014

Abstract excerpt

The incidence of cancer is increasing worldwide, but the biochemical mechanisms for the occurrence of cancer is not fully understood, and there is no cure for advanced tumors. Defects of posttranslational modifications of proteins are linked to a number of important diseases, such as cancer. This review will update our knowledge on the critical role of posttranscriptional regulation of phosphatase and tensin...

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PMID: 25336918
DOI: 10.2147/dddt.s71061

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