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Article

JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress.

Scientific reports - 28 Feb 2018

Myers Toshia R, Amendola Pier Giorgio, Lussi Yvonne C, Salcini Anna Elisabetta

Abstract excerpt

Post-translational modifications of histones, constitutive components of chromatin, regulate chromatin compaction and control all DNA-based cellular processes. C. elegans JMJD-1.2, a member of the KDM7 family, is a demethylase active towards several lysine residues on Histone 3 (H3), but its contribution in regulating histone methylation in germ cells has not been fully investigated. Here, we show that jmjd-1.2...

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Identifiers

PMID: 29491442
DOI: 10.1038/s41598-018-21914-9
PMCID: PMC5830613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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