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Article

MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells.

Cell research - 1 May 2012

Xu Jing, Sun Xiaojuan, Jing Yudong, Wang Mo, Liu Kai, Jian Youli, Yang Mei, Cheng Zhukuan, Yang Chonglin

Abstract excerpt

During meiotic cell division, proper chromosome synapsis and accurate repair of DNA double strand breaks (DSBs) are required to maintain genomic integrity, loss of which leads to apoptosis or meiotic defects. The mechanisms underlying meiotic chromosome synapsis, DSB repair and apoptosis are not fully understood. Here, we report that the chromodomain-containing protein MRG-1 is an important factor for genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22212480
DOI: 10.1038/cr.2012.2
PMCID: PMC3343660

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MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells.PMID 22212480Read ↗

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