Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery.

Genome biology - 7 Feb 2018

Lee Heewook, Kingsford Carl

Abstract excerpt

Accurate typing of human leukocyte antigen (HLA) is important because HLA genes play important roles in immune responses and disease genesis. Previously available computational methods are database-matching approaches and their outputs are inherently limited by the completeness of already known types, making them unsuitable for discovery of novel alleles. We have developed a graph-guided assembly technique for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genome
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Testing

Share to HLA Antigens

Share to Terminology as Topic

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 29415772
DOI: 10.1186/s13059-018-1388-2
PMCID: PMC5804087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery.PMID 29415772Read ↗

Graph-guided assembly for novel HLA allele discoverySemantic proximity Read ↗

Accurate Assembly and Typing of HLA using a Graph-Guided Assembler Kourami.Semantic proximity Read ↗

Accurate HLA type inference using a weighted similarity graph.Semantic proximity Read ↗

Full-resolution HLA and KIR gene annotations for human genome assemblies.Semantic proximity Read ↗

Full resolution HLA and KIR genes annotation for human genome assembliesSemantic proximity Read ↗

HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data.Semantic proximity Read ↗

Benchmarking freely available human leukocyte antigen typing algorithms across varying genes, coverages and typing resolutionsSemantic proximity Read ↗

NovoGraph: Human genome graph construction from multiple long-read de novo assembliesSemantic proximity Read ↗

A pan-MHC reference graph with 246 fully contiguous phased sequencesSemantic proximity Read ↗

HLA*LA—HLA typing from linearly projected graph alignmentsSemantic proximity Read ↗

HLA type inference via haplotypes identical by descent.Semantic proximity Read ↗

TypeAssembly: Copy number estimation and allele typing for haplotype assembliesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.