Article
HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data.
Human mutation - 1 Jul 2017
Kawaguchi Shuji, Higasa Koichiro, Shimizu Masakazu, Yamada Ryo, Matsuda Fumihiko
Abstract excerpt
The accurate typing of human leukocyte antigen (HLA) alleles is critical for a variety of medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation-related disorders, and donor selection in organ transplantation and regenerative medicine. H...
Topics
- Algorithms
- Alleles
- Chromosome Mapping
- Cloning, Molecular
- Computational Biology
- DNA Primers
- Databases, Factual
- Exons
- Genome, Human
- Genomics
- HLA Antigens
- High-Throughput Nucleotide Sequencing
- Histocompatibility Testing
- Humans
- Models, Statistical
- Polymerase Chain Reaction
- Pseudogenes
- Reproducibility of Results