Article
HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data.
Human mutation - 1 Jul 2017
Kawaguchi Shuji, Higasa Koichiro, Shimizu Masakazu, Yamada Ryo, Matsuda Fumihiko
Abstract excerpt
The accurate typing of human leukocyte antigen (HLA) alleles is critical for a variety of medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation-related disorders, and donor selection in organ transplantation and regenerative medicine. Here, we developed a new algorithm for determining HLA alleles using next-generation sequencing (NGS) results. The...
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