Article

Graph-guided assembly for novel HLA allele discovery

2017-05-17

Abstract excerpt

Accurate typing of human leukocyte antigen (HLA), a histocompatibility test, is important because HLA genes play various roles in immune responses, and have also been shown to be associated with many diseases such as cancer. The current gold standard for HLA typing uses DNA sequencing technology combined with sequence enrichment techniques using specially designed primers or probes, causing it to be slow and labor...

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Literature Corpus work: 1994ae53-5d47-5f2d-8004-9249c6f9880f
DOI: 10.1101/138826

Open publication

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