Article

NovoGraph: Human genome graph construction from multiple long-read de novo assemblies

2018-12-10

Abstract excerpt

Genome graphs are emerging as an important novel approach to the analysis of high-throughput human sequencing data. By explicitly representing genetic variants and alternative haplotypes in a mappable data structure, they can enable the improved analysis of structurally variable and hyperpolymorphic regions of the genome. In most existing approaches, graphs are constructed from variant call sets derived from short...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1ce824d9-9356-5721-b117-75f4bf34eeee
DOI: 10.12688/f1000research.15895.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NovoGraph: Human genome graph construction from multiple long-read de novo assembliesDOI 10.12688/f1000research.15895.2Read

Fast and Accurate Genomic Analyses using Genome GraphsSemantic proximity Read

Rapid, accurate long- and short-read mapping to large pangenome graphs with vg GiraffeSemantic proximity Read

Genome Graphs and the Evolution of Genome InferenceSemantic proximity Read

Pangenome Graph Construction from Genome Alignment with Minigraph-CactusSemantic proximity Read

Rapid, accurate long- and short-read mapping to large pangenome graphs with vg GiraffeSemantic proximity Read

Genome GraphsSemantic proximity Read

Graphtyper: Population-scale genotyping using pangenome graphsSemantic proximity Read

Pangenomics enables genotyping of known structural variants in 5202 diverse genomes.Semantic proximity Read

Graphtyper enables population-scale genotyping using pangenome graphs.Semantic proximity Read

ConnectedReads: machine-learning optimized long-range genome analysis workflow for next-generation sequencingSemantic proximity Read

Genotyping common, large structural variations in 5,202 genomes using pangenomes, the Giraffe mapper, and the vg toolkitSemantic proximity Read

GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs.Semantic proximity Read