Article

Full resolution HLA and KIR genes annotation for human genome assemblies

2024-01-23

Abstract excerpt

The HLA (Human Leukocyte Antigen) genes and the KIR (Killer cell Immunoglobulin-like Receptor) genes are critical to immune responses and are associated with many immune-related diseases. Located in highly polymorphic regions, they are hard to be studied with traditional short-read alignment-based methods. Although modern long-read assemblers can often assemble these genes, using existing tools to annotate HLA and...

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Literature Corpus work: 0c60904f-3d60-5af7-82b2-d9ad4feb2527
DOI: 10.1101/2024.01.20.576452

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