Article
Accurate HLA type inference using a weighted similarity graph.
BMC bioinformatics - 14 Dec 2010
Xie Minzhu, Li Jing, Jiang Tao
Abstract excerpt
BACKGROUND: The human leukocyte antigen system (HLA) contains many highly variable genes. HLA genes play an important role in the human immune system, and HLA gene matching is crucial for the success of human organ transplantations. Numerous studies have demonstrated that variation in HLA genes i...
Topics
- Algorithms
- Alleles
- Genotype
- HLA Antigens
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Haplotypes
- Histocompatibility Testing
- Humans
- Polymorphism, Single Nucleotide