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Article

Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly.

Brain imaging and behavior - 1 Feb 2019

Shu Hao, Shi Yongmei, Chen Gang, Wang Zan, Liu Duan, Yue Chunxian, Ward B Douglas, Li Wenjun, Xu Zhan, Chen Guangyu, Guo Qi-Hao, Xu Jun, Li Shi-Jiang, Zhang Zhijun

Abstract excerpt

The apolipoprotein E (APOE) ε4 and ε2 alleles are acknowledged genetic factors modulating Alzheimer's disease (AD) risk and episodic memory (EM) deterioration in an opposite manner. Mounting neuroimaging studies describe EM-related brain activity differences among APOE alleles but remain limited in elucidating the underlying mechanism. Here, we hypothesized that the APOE ε2, ε3, and ε4 alleles have distinct EM...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29396739
DOI: 10.1007/s11682-017-9818-4
PMCID: PMC8061791

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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