Article
The effects of APOE on the functional architecture of the resting brain.
NeuroImage - 2 Jan 2012
Trachtenberg Aaron J, Filippini Nicola, Ebmeier Klaus P, Smith Steve M, Karpe Fredrik, Mackay Clare E
Abstract excerpt
There is a well-established association between APOE genotype and the risk of developing Alzheimer's disease (AD). Relative to individuals with the common ε3/ε3 genotype, carriers of the ε4 allele are at increased risk of developing AD, while carriers of the ε2 allele appear to be protected against the disease. However, we recently reported that in a sample of cognitively healthy adults, both ε4 and ε2 carriers...
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