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Article

Differential effects of the ApoE4 genotype on brain structure and function.

NeuroImage - 1 Apr 2014

Matura Silke, Prvulovic David, Jurcoane Alina, Hartmann Daniel, Miller Julia, Scheibe Monika, O'Dwyer Laurence, Oertel-Knöchel Viola, Knöchel Christian, Reinke Britta, Karakaya Tarik, Fußer Fabian, Pantel Johannes

Abstract excerpt

The apolipoprotein E ε4 allele is a well established genetic risk factor for sporadic Alzheimer's disease. It is associated with structural and functional brain changes in healthy young, middle-aged and elderly subjects. In the current study, we assessed the impact of the ApoE genotype on brain macro- and microstructure, cognitive functioning and brain activity in fifty healthy young subjects (25 ApoE ε4 (ε4+)...

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Apolipoprotein E4
Brain
Brain Mapping
Diffusion Tensor Imaging
Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Memory, Episodic

Neuropsychological Tests

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PMID: 24296331
DOI: 10.1016/j.neuroimage.2013.11.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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