Article
Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers.
Cerebral cortex (New York, N.Y. : 1991) - 1 Aug 2007
Mondadori Christian R A, de Quervain Dominique J-F, Buchmann Andreas, Mustovic Henrietta, Wollmer M Axel, Schmidt Conny F, Boesiger Peter, Hock Christoph, Nitsch Roger M, Papassotiropoulos Andreas, Henke Katharina
Abstract excerpt
The apolipoprotein E (APOE) epsilon4 allele is the major genetic risk factor for Alzheimer's disease, but an APOE effect on memory performance and memory-related neurophysiology in young, healthy subjects is unknown. We found an association of APOE epsilon4 with better episodic memory compared with APOE epsilon2 and epsilon3 in 340 young, healthy persons. Neuroimaging was performed in a subset of 34...
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