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Article

Peptidyl-prolyl isomerase Pin1 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in ApoE-/- mice.

Journal of molecular and cellular cardiology - 1 Jan 2018

Liang Er-Shun, Cheng Wen, Yang Rui-Xue, Bai Wen-Wu, Liu Xue, Zhao Yu-Xia

Abstract excerpt

Peptidyl-prolyl isomerase Pin1 has been reported to be associated with endothelial dysfunction. However, the role of smooth muscle Pin1 in the vascular system remains unclear. Here, we examined the potential function of Pin1 in smooth muscle cells (SMCs) and its contribution to abdominal aortic aneurysm (AAA) pathogenesis. The level of Pin1 expression was found to be elevated in human AAA tissues and mainly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kruppel-Like Factor 4

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Source

Identifiers

PMID: 29269260
DOI: 10.1016/j.yjmcc.2017.12.006

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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