Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Catechol-O-methyltransferase, Cognition and Alzheimer's Disease

12 Dec 2017

Abstract excerpt

OBJECTIVE: Cognition is a complex trait representing a set of all mental abilities and processes related to knowledge. Although diverse brain regions are involved, most cognitive processes appear to engage cortical regions. The activity of dopaminergic neurons in prefrontal cortex represents a biological substrate underlying cognitive functions. Alzheimer's Disease (AD) is the most frequent dementia associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dementia and Cognitive Impairment Research
Share to Neurotransmitter Receptor Influence on Behavior
Share to Phosphodiesterase function and regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29231139
DOI: 10.2174/1567205015666171212094229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Catechol-O-methyltransferase, Cognition and Alzheimer's DiseasePMID 29231139Read ↗

Catechol-o-methyltransferase and Alzheimer's disease: a review of biological and genetic findings.Semantic proximity Read ↗

Association study of a functional catechol-o-methyltransferase polymorphism and cognitive function in patients with dementia.Semantic proximity Read ↗

Catechol-o-methyl transferase modulates cognition in late life: evidence and implications for cognitive enhancement.Semantic proximity Read ↗

Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.Semantic proximity Read ↗

Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics.Semantic proximity Read ↗

Catechol-O-methyltransferase val158met and cognitive function in Parkinson's disease.Semantic proximity Read ↗

Catechol-O-methyltransferase gene polymorphism is associated with risk of psychosis in Alzheimer Disease.Semantic proximity Read ↗

Influence of COMT polymorphism in cognitive performance on dementia in community-dwelling elderly Mexican (SADEM study).Semantic proximity Read ↗

Association between polymorphism of COMT gene (Val158Met) with Alzheimer's disease: An updated analysis.Semantic proximity Read ↗

Association study of a functional catechol-O-methyltransferase polymorphism and executive function in elderly males without dementia.Semantic proximity Read ↗

Association between the catechol-O-methyltransferase polymorphism Val158Met and Alzheimer's disease in a Japanese population.Semantic proximity Read ↗

Influence of COMT Val158Met polymorphism on Alzheimer's disease and mild cognitive impairment in Italian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.