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Influence of COMT polymorphism in cognitive performance on dementia in community-dwelling elderly Mexican (SADEM study).

Metabolic brain disease - 1 Aug 2021

Juárez-Cedillo Teresa, González-Figueroa Evangelina, Martínez-Rodríguez Nancy, Fragosos Jose M, Garrido-Acosta Osvaldo, Vargas-Alarcón Gilberto

Abstract excerpt

There is an inconsistent finding about the relationship of catechol-O-methyltransferase (COMT) with dementia susceptibility, as well as with cognitive impairment. To substantiate this, we examined COMT genotype effects in certain cognitive domains in dementia. To evaluate the effects of COMT Val158Met on cognitive performance, we used The Mini-Mental State Examination (MMSE), the cognitive subscale of the...

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Identifiers

PMID: 33900525
DOI: 10.1007/s11011-021-00740-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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