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Article

Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.

Biological psychiatry - 15 Jul 2008

Barnett Jennifer H, Scoriels Linda, Munafò Marcus R

Abstract excerpt

BACKGROUND: Cognitive endophenotypes may further our understanding of the genetic basis of psychiatric disorders, and the catechol-O-methyltransferase (COMT) gene is a promising candidate gene for both cognitive function and disorder. We conducted a meta-analysis of reported associations between the COMT Val158/108Met polymorphism and measures of memory and executive function. METHODS: The PubMed database was...

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Catechol O-Methyltransferase
Cognition Disorders
Intelligence
Memory Disorders
Neuropsychological Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Problem Solving

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PMID: 18339359
DOI: 10.1016/j.biopsych.2008.01.005

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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