Article

Improved Allele Frequencies in gnomAD through Local Ancestry Inference

2024-10-31

Abstract excerpt

The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation. However, traditional estimates rely on individual-level genetic ancestry groupings that may obscure variation in recently admixed populations. To improve resolution, we applied local ancestry inference (LAI) to over 27 million variants in two admixed groups: Ad...

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Literature Corpus work: 450b084a-318c-578b-a99b-0b24e6fb4617
DOI: 10.1101/2024.10.30.620961

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