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Article

Development of a new biochip array for APOE4 classification from plasma samples using immunoassay-based methods.

Clinical chemistry and laboratory medicine - 25 Apr 2018

Badrnya Sigrun, Doherty Tara, Richardson Ciaran, McConnell Robert I, Lamont John V, Veitinger Michael, FitzGerald Stephen P, Zellner Maria, Umlauf Ellen

Abstract excerpt

BACKGROUND: Apolipoprotein E (APOE) is a key player in lipid transport and metabolism and exists in three common isoforms: APOE2, APOE3 and APOE4. The presence of the E4 allelic variant is recognized as a major genetic risk factor for dementia and other chronic (neuro)degenerative diseases. The availability of a validated assay for rapid and reliable APOE4 classification is therefore advantageous. METHODS:...

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Source

Identifiers

PMID: 29220880
DOI: 10.1515/cclm-2017-0618

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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