Article

Robust Serum Proteomic Signatures of APOE2

2025-05-29

Abstract excerpt

We previously identified a signature of 16 serum proteins that highlighted a role of the e2 allele of APOE in lipid regulation via apolipoprotein B (APOB) and apolipoprotein E (APOE), and in inflammation. The serum proteins were profiled using the aptamer-based Somalogic technology. Here, we validate and expand the serum protein signature of APOE using a combination of mass-spectrometry, ELISA, Luminex, antibody-b...

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Literature Corpus work: 07f6047b-4218-5e0d-af72-2d4cfff10dc8
DOI: 10.1101/2025.05.24.655950

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