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Article

A fast and cost-effective method for apolipoprotein E isotyping as an alternative to APOE genotyping for patient screening and stratification.

Scientific reports - 13 Apr 2018

Calero Olga, García-Albert Luis, Rodríguez-Martín Andrés, Veiga Sergio, Calero Miguel

Abstract excerpt

Apolipoprotein E (apoE) is a 34 kDa glycoprotein involved in lipid metabolism. The human APOE gene encodes for three different apoE protein isoforms: E2, E3 and E4. The interest in apoE isoforms is high for epidemiological research, patient stratification and identification of those at increased risk for clinical trials and prevention. The isoform apoE4 is associated with increased risk for coronary heart and...

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Alzheimer Disease
Antibodies, Monoclonal
Apolipoproteins E
Coronary Disease
Cost-Benefit Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Isoforms

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Identifiers

PMID: 29654261
DOI: 10.1038/s41598-018-24320-3
PMCID: PMC5899170

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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