Article
Dependency of Heterochromatin Domains on Replication Factors.
G3 (Bethesda, Md.) - 2 Feb 2018
Jahn Leonie Johanna, Mason Bethany, Brøgger Peter, Toteva Tea, Nielsen Dennis Kim, Thon Genevieve
Abstract excerpt
Chromatin structure regulates both genome expression and dynamics in eukaryotes, where large heterochromatic regions are epigenetically silenced through the methylation of histone H3K9, histone deacetylation, and the assembly of repressive complexes. Previous genetic screens with the fission yeast Schizosaccharomyces pombe have led to the identification of key enzymatic activities and structural constituents of...
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