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Article

Rapid epigenetic adaptation to uncontrolled heterochromatin spreading.

eLife - 16 Mar 2015

Wang Jiyong, Reddy Bharat D, Jia Songtao

Abstract excerpt

Heterochromatin, a highly compact chromatin state characterized by histone H3K9 methylation and HP1 protein binding, silences the underlying DNA and influences the expression of neighboring genes. However, the mechanisms that regulate heterochromatin spreading are not well understood. In this study, we show that the conserved Mst2 histone acetyltransferase complex in fission yeast regulates histone turnover at...

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Identifiers

PMID: 25774602
DOI: 10.7554/eLife.06179
PMCID: PMC4395908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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