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Article

Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

Andrology - 1 Jan 2018

Bang A K, Busch A S, Almstrup K, Gromoll J, Kliesch S, Rajpert-De Meyts E, Skakkebaek N E, Juul A, Tüttelmann F, Jørgensen N

Abstract excerpt

Testicular germ cell cancer (TGCC) is derived from germ cell neoplasia in situ (GCNIS), which arises due to niche disturbances affecting the Sertoli cells. It is believed that exogenous endocrine factors have a crucial role in governing neoplastic transformation but on a strong hereditary background. Follicle-stimulating hormone (FSH) is the major regulatory hormone of the Sertoli cells. FSH signalling-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Germ Cell and Embryonal

Share to Polymorphism, Single Nucleotide

Share to Receptors, FSH

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Source

Identifiers

PMID: 29179257
DOI: 10.1111/andr.12440

Genes

FSHR
FSHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?PMID 29179257Read ↗

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