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Article

Mechanisms in endocrinology: Genetics of FSH action: a 2014-and-beyond view.

European journal of endocrinology - 1 Mar 2014

Simoni Manuela, Casarini Livio

Abstract excerpt

OBJECTIVE: To assess the pharmacogenetic potential of FSH for infertility treatment. DESIGN: Review of the literature and genomic databases. METHODS: Single-nucleotide polymorphism (SNP) assessed: rs6166 (c.2039A>G, p.N680S), rs6165 (c.919A>G, p.T307A), rs1394205 (c.-29G>A) in FSHR, and rs10835638 (c.-211G>T) in FSHB. Literature search via PubMed. Blast analysis of genomic information available in the NCBI...

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Topics

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Share to Genetics, Population
Share to Follicle Stimulating Hormone, beta Subunit
Share to Infertility
Share to Ovulation Induction
Share to Pharmacogenetics
Share to Promoter Regions, Genetic
Share to Receptors, FSH
Share to Reproductive Techniques, Assisted

Source

Identifiers

PMID: 24288354
DOI: 10.1530/EJE-13-0624

Genes

FSHR
FSHB

Variants

rs6166
rs6165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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