Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FSHB -211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women.

Human reproduction (Oxford, England) - 1 May 2018

Rull Kristiina, Grigorova Marina, Ehrenberg Aivar, Vaas Pille, Sekavin Aire, Nõmmemees Diana, Adler Mart, Hanson Ele, Juhanson Peeter, Laan Maris

Abstract excerpt

STUDY QUESTION: Are the genetic variants FSHB -211 G>T (rs10835638), FSHR c.2039 A>G (Asn680Ser, rs6166) and FSHR -29 G>A (rs1394205) associated with serum FSH, LH and anti-Müllerian hormone (AMH) levels in reproductive age women, their menstrual cycle parameters and risk of infertility? SUMMARY ANSWER: Only the FSHB -211 G>T variant was a major genetic determinant of serum gonadotropin levels in both,...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Mullerian Hormone
Share to Fertility
Share to Follicle Stimulating Hormone
Share to Follicle Stimulating Hormone, beta Subunit
Share to Infertility, Female
Share to Luteinizing Hormone
Share to Menstrual Cycle
Share to Reproduction

Source

Identifiers

PMID: 29617818
DOI: 10.1093/humrep/dey057

Genes

FSHB
FSHR
AMH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FSHB -211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women.PMID 29617818Read ↗

Effects of the FSH-β-subunit promoter polymorphism -211G->T on the hypothalamic-pituitary-ovarian axis in normally cycling women indicate a gender-specific regulation of gonadotropin secretion.Semantic proximity Read ↗

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health.Semantic proximity Read ↗

The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age.Semantic proximity Read ↗

Mechanisms in endocrinology: Genetics of FSH action: a 2014-and-beyond view.Semantic proximity Read ↗

Reproductive physiology in young men is cumulatively affected by FSH-action modulating genetic variants: FSHR -29G/A and c.2039 A/G, FSHB -211G/T.Semantic proximity Read ↗

Effects of a Polymorphism in the Promoter Region of the Follicle-Stimulating Hormone Subunit Beta ( FSHB ) Gene on Female Reproductive OutcomesSemantic proximity Read ↗

Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls.Semantic proximity Read ↗

Pharmacogenetics of FSH Action in the FemaleSemantic proximity Read ↗

Effects of FSHR and FSHB Variants on Hormonal Profile and Reproductive Outcomes of Infertile Women With Endometriosis.Semantic proximity Read ↗

The FSHB -211G>T variant attenuates serum FSH levels in the supraphysiological gonadotropin setting of Klinefelter syndrome.Semantic proximity Read ↗

Increased Prevalance of the -211 T allele of follicle stimulating hormone (FSH) beta subunit promoter polymorphism and lower serum FSH in infertile men.Semantic proximity Read ↗

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause, and impact reproductive health: a UK Biobank studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.