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Article

Association of polymorphisms in genes encoding hormone receptors ESR1, ESR2 and LHCGR with the risk and clinical features of testicular germ cell cancer.

Molecular and cellular endocrinology - 4 Apr 2012

Brokken Leon J S, Lundberg-Giwercman Yvonne, Rajpert De-Meyts Ewa, Eberhard Jakob, Ståhl Olof, Cohn-Cedermark Gabriella, Daugaard Gedske, Arver Stefan, Giwercman Aleksander

Abstract excerpt

Testicular germ cell cancer (TGCC) is the most common malignancy in young men. Genetic variants known to be associated with risk of TGCC only partially account for the observed familial risks. We aimed to identify additional polymorphisms associated with risk as well as histological and clinical...

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Topics

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Share to Androgen-Insensitivity Syndrome
Share to Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follicle Stimulating Hormone

Share to Luteinizing Hormone

Share to Neoplasms, Germ Cell and Embryonal

Share to Receptors, LH

Share to Sex Hormone-Binding Globulin

Share to Testicular Neoplasms

Source

Identifiers

PMID: 22245602
DOI: 10.1016/j.mce.2011.12.018

Genes

LHCGR
ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22245602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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